Abstract: Signaling pathway is the way by which cells receive various stimulation signals, and produce a series of corresponding responses, such as cell proliferation, differentiation and apoptosis. During infection with Echinococcus multilocularis, both parasite and host cells may secrete many cytokines such as insulin, which make stimulating signals transmitted into the cells through their receptors on the surface of cells. As a result, the parasite can grow and proliferate in the host. Study on related signaling pathways and their blocking drugs will play a crucial role in the control of alveolar echinococcosis caused by the larvae of E. multilocularis.

Key words: Echinococcus multilocularis, Signaling pathway, Cytokine, Receptor, Therapeutic drug