Application of metabolomics in research of medical helminths

doi:10.12140/j.issn.1000-7423.2021.05.020

Abstract

Abstract:

Metabolomics is a new type of omics that rapidly developed after genomics, transcriptomics and proteomics. Because of its unique advantages, metabolomics has been applied in early diagnosis of diseases, discovery of drug targets, and for understanding animal and plant metabolisms. Metabolomics has been increasingly using in studies of paras ites, focusing on parasites’ metabolism, screening diagnostic biomarkers and revealing mechanism of drug actions, to provide new ideas for exploring parasite-host interaction, and for further understanding of diagnosis and treatment of parasitic diseases. In this review, we summarize metabolomics associated research methodologies, and advances of their applications in studies of medical helminths, to provide reference for wider application of metabolomics in parasitology research.

Key words: Medical helminths, Metabolomics, Current applications

CLC Number:

R383

HU Yue, LV Zhi-yue. Application of metabolomics in research of medical helminths[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2021, 39(5): 703-709.

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