Immunomodulatory Effect of Trichinella spiralis and its Derivative#br#
Products in Allergy and Autoimmune Diseases

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Immunomodulatory Effect of Trichinella spiralis and its Derivative#br# Products in Allergy and Autoimmune Diseases

DING Yi-han，WANG Xiao-li，SONG Di，WU Qi，YANG Xiao-di*

Department of Microbiology and Parasitology，Anhui Key Laboratory of Infection and Immunity，Bengbu Medical College，Bengbu 233030，China

Online:2016-08-30 Published:2016-11-07

Abstract

Abstract:

Trichinella spiralis and its derivative antigens stimulate T cell activation by inducing dendritic cell semimaturation, thereby regulating the Th1/Th2 type immune response and alleviating or inhibiting allergy and autoimmune diseases. The regulatory T cell and anti-inflammatory factors play important roles in this immunomodulatory process. This article reviews the modulatory effects and their mechanisms of Trichinella spiralis and its derivatives in autoimmune disorders.

Key words: Trichinella spiralis, Regulation, Allergy, Autoimmune disease

DING Yi-han，WANG Xiao-li，SONG Di，WU Qi，YANG Xiao-di*. Immunomodulatory Effect of Trichinella spiralis and its Derivative#br# Products in Allergy and Autoimmune Diseases[J]. .

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Immunomodulatory Effect of Trichinella spiralis and its Derivative#br# Products in Allergy and Autoimmune Diseases

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