Research advances of the immune regulation of helminths and their derived molecules on mite-induced asthma

doi:10.12140/j.issn.1000-7423.2023.02.001

Abstract

Abstract:

With the improvement of living hygiene, the helminth infection rate has declined, and people have entered the post-parasite stage. But at the same time, the incidence rate of mite-induced asthma is increasing, which has caused a significant social and economic burden. Increasing evidence showed a correlation between helminth infection and allergy. This article reviews the regulation of helminth and their derived molecules on the occurrence and development of mite-induced asthma, including the direct regulation of antigen-presenting cells, humoral immunity, cellular immunity, release and action of cytokines, and the indirect regulation by regulating intestinal microflora, providing new ideas and directions for the treatment of mites-induced asthma.

Key words: Helminth, Helminth derived molecules, Immune regulation, Mite-allergic asthma

CLC Number:

R383

LI Wenjie, FENG Meng, CHENG Xunjia. Research advances of the immune regulation of helminths and their derived molecules on mite-induced asthma[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2023, 41(2): 131-136.

Figures/Tables 1

References 57

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