Study Progress on Mefloquine against Schistosomes and other Helminths

›› 2012, Vol. 30 ›› Issue (2): 10-131-138,145.

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Study Progress on Mefloquine against Schistosomes and other Helminths

XIAO Shu-Hua, XUE Jian

National Institute of Parasitic Diseases，Chinese Center for Disease Control and Prevention；Key Laboratory of Parasite and Vector Biology，MOH；WHO Collaborating Centre for Malaria，Schistosomiasis and Filariasis，Shanghai 200025，China

Online:2012-04-30 Published:2012-09-28

Abstract

Abstract: 【Abstract】 In recent years，antimalarial drug mefloquine，an amino alcohol compound，has been found to exhibit potential effect against schistosomes. The feature of antischistosomal properties of mefloquine is that the drug possesses similar killing effect against various development stages of juvenile and adult schistosomes. This paper summarizes the recent three years′ progress in experimental studies of mefloquine against schistosomes and other helminthes.

Key words: Mefloquine, Amino-alcohol compound, Schistosoma mansoni, Schistosoma japonicum, Trematode, Echinococcus multilocularis, Praziquantel

XIAO Shu-Hua, XUE Jian. Study Progress on Mefloquine against Schistosomes and other Helminths[J]. , 2012, 30(2): 10-131-138,145.

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Study Progress on Mefloquine against Schistosomes and other Helminths

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