Research progress on the pathogenesis and control of clonorchiasis

CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES ›› 2025, Vol. 43 ›› Issue (4): 567-574.doi: 10.12140/j.issn.1000-7423.2025.04.018

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Research progress on the pathogenesis and control of clonorchiasis

LI Pange(), FU Jinghua, XU Minjun*()   

  1. College of Marine Sciences, South China Agricultural University, Provincial Modern Agriculture (Aquatic Product Quality and Safety) Industrial Technology R&D Center of South China Agricultural University, Guangzhou 510642, Guangdong, China
  • Received:2024-12-11 Revised:2025-04-20 Online:2025-08-30 Published:2025-10-09
  • Contact: E-mail: xuminjun@scau.edu.cn
  • Supported by:
    Competitive Selection Program for “Major Special Projects + Task List”(220720171471924)

Abstract:

Clonorchis sinensis is an important zoonotic parasite with fish and shrimp as intermediate hosts and mammals as definitive hosts, which mainly causes digestive diseases, such as cholangiocarcinoma. With improvements of residents’ consumption level and changes of consumption structure in China, the number of human clonorchiasis cases caused by consuming raw or half cooked fish reaches up to more than 13 million in China, and clonorchiasis has become an urgent problem to be solved in the field of food safety and public health. This article reviews the latest international and national advances in the pathogenesis and prevention and control measures of C. sinensis infection in recent years, so as to provide insights into surveillance, prevention and control of this pathogen.

Key words: Clonorchis sinensis, Pathogenesis, Fish, Prevention and control

CLC Number: