中国寄生虫学与寄生虫病杂志 ›› 2023, Vol. 41 ›› Issue (3): 374-379.doi: 10.12140/j.issn.1000-7423.2023.03.017
收稿日期:
2022-10-12
修回日期:
2023-04-24
出版日期:
2023-06-30
发布日期:
2023-05-30
通讯作者:
*陈军虎(1978-),男,博士,研究员,从事重要媒传寄生虫感染与宿主免疫、诊断、疫苗研究。E-mail:chenjh@nipd.chinacdc.cn
作者简介:
徐少杰(1997-),男,硕士研究生,从事寄生虫病防治研究。E-mail:xushaojie0420@163.com
基金资助:
XU Shaojie(), CHEN Shenbo, CHEN Junhu*()
Received:
2022-10-12
Revised:
2023-04-24
Online:
2023-06-30
Published:
2023-05-30
Contact:
*E-mail: Supported by:
摘要:
恶性疟原虫在人体内编码变异型表面抗原,可能引起其对人体进行免疫逃避。重复散布家族(rif)基因是编码变异型表面抗原的第一大家族,研究rif基因的调控如组蛋白修饰、阻遏元件调节、表达蛋白参与了免疫逃避等,具有很重要的意义。本文对调控rif基因机制的相关的研究进展进行综述,以期探究恶性疟原虫的致病过程。
中图分类号:
徐少杰, 陈绅波, 陈军虎. 恶性疟原虫重复散布家族基因转录调控的研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2023, 41(3): 374-379.
XU Shaojie, CHEN Shenbo, CHEN Junhu. Research progress on transcription regulation of rif gene in Plasmodium falciparum[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2023, 41(3): 374-379.
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