Alveolar echinococcosis and immune evasion

Abstract

Abstract:

Alveolar echinococcosis （AE） is a zoonotic parasitic disease that has a worldwide distribution and seriously threatens human health and husbandry. In recent years, the immune escape mechanism of AE has become a research hotspot. This review is focused on the immune escape mechanisms from perspectives of self-antigen alteration, cytotoxicity, negative immune regulation, alteration of types of immune response, induction of immune cell apoptosis, immunosuppression, and innate immunity and genetic background of the host, in order to provide novel insights into echinococcosis.

Key words: Alveolar echinococcosis, Immune evasion, Mechanism

CLC Number:

R532.32

Han-dong LIU, Hong-bing WANG, Hai-ning FAN, Hai-feng NIU, Zhi-xin WANG. Alveolar echinococcosis and immune evasion[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2018, 36(6): 655-660.

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