CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES ›› 2018, Vol. 36 ›› Issue (6): 648-654.

• Orginal Article • Previous Articles     Next Articles

Research progress on extracellular vesicles of helminthes

Xiao-fan ZHANG, Wen-ci GONG, Yu-juan SHEN*()   

  1. National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research; WHO Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology; Key Laboratory of Parasite and Vector Biology, Ministry of Health, Shanghai 200025, China
  • Received:2018-07-02 Online:2018-12-30 Published:2019-01-08
  • Contact: Yu-juan SHEN E-mail:shenyj@nipd.chinacdc.cn
  • Supported by:
    Supported by the National Natural Science Foundation of China (No. 81772224, No. 81772225)

Abstract:

Extracellular vesicles are vesicular bodies secreted by a variety of cells and contain large amounts of biologically active substances such as proteins, lipids and nucleic acids. They are widely involved in intercellular substance exchange and information transmission. Studies have shown that parasites can conduct intercellular communications and transfer a series of biologically active molecules to host cells through extracellular vesicles to regulate the host immune system. This review summarizes the research progress on extracellular vesicles in parasitic helminthes, in order to provide new ideas for the study of extracellular vesicles in the field of parasites.

Key words: Extracellular vesicle, Helminth, Host, Interaction mechanism

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