Advances in research on Nod-like receptor protein 3 inflammasome in parasitic diseases

doi:10.12140/j.issn.1000-7423.2020.03.021

Abstract

Abstract:

Inflammatory corpuscles are receptors of the innate immune system and participate in the stress responses against pathogenic organisms after activated. This review summarizes the basic structure and functions of Nod-like receptor protein 3 (NLRP3) inflammasome as well as the related researches on malaria, amoebic disease, trypanosomiasis, leishmaniasis, schistosomiasis, and vaginal trichomoniasis, aiming to analyze the role and mechanism of NLRP3 inflammasome in parasitic diseases and provide ideas for better interventions and treatment.

Key words: Parasitic disease, Nod-like receptor protein 3 inflammasome, Inflammation, Immune response

CLC Number:

CHEN Cai-song, ZHANG Yao-gang, WANG Zhi-xin, FAN Hai-ning. Advances in research on Nod-like receptor protein 3 inflammasome in parasitic diseases[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2020, 38(3): 390-394.

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