CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES ›› 2023, Vol. 41 ›› Issue (1): 98-102.doi: 10.12140/j.issn.1000-7423.2023.01.015

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Advances in parasite epitope vaccine research

WU Xiaoying(), HU Yuan*(), CAO Jianping   

  1. National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research); NHC Key Laboratory of Parasite and Vector Biology; National Health Commission, WHO Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases; Shanghai 200025, China
  • Received:2022-05-18 Revised:2022-06-24 Online:2023-02-28 Published:2023-02-22
  • Contact: * E-mail: huyuan@nipd.chinacdc.cn
  • Supported by:
    Natural Science Foundation of Shanghai(19ZR1462600);Surface Project of National Natural Science Foundation of China(81971969)

Abstract:

Parasitic diseases not only seriously threaten human health, but also cause huge economic losses to animal husbandry. At present, developing safe and effective vaccines is one of the strategies for the prevention and control of parasitic diseases. Epitope vaccine has the advantages of high specificity, safety, flexible design, easy production and storage, and can induce humoral and cellular immunity simultaneously. In recent years, great progress had been made in the epitope vaccines for parasitic diseases. This paper have reviewed the recent advances of vaccine epitope design and related vaccine research in parasitic diseases, in order to provide reference for the further development of effective vaccines.

Key words: Parasitic diseases, Epitope vaccine, Epitope design, Synthetic peptide vaccine

CLC Number: