›› 2012, Vol. 30 ›› Issue (5): 13-401-405.

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Research Advances in Interplay of Host Immune Mechanism and Echinococcus multilocularis Metacestodes

LOU Zhong-zi,LI Hong-min,YAN Hong-bin,NI Xing-wei,JIA Wan-zhong*   

  1. State Key Laboratory of Veterinary Etiological Biology;Key Laboratory of Veterinary Parasitology of Gansu Province;Key Laboratory of Grazing Animal Diseases of Ministry of Agriculture;Key Laboratory of Veterinary Public Health of Ministry of Agriculture;Lanzhou Veterinary Research Institute;Chinese Academy of Agricultural Sciences,Lanzhou 730046, China
  • Online:2012-10-30 Published:2013-02-05

Abstract: 【Abstract】  Through affecting on host innate and acquired immune responses, Echinococcus multilocularis orchestrates various interplays that are beneficial not only to facilitate its intrahepatic proliferation and maturation during life cycle, but also to limit pathological process in its intermediate host. This review reveals the role of the metacestode′s immune-related molecules in modulating host responses and optimizing its own survival.

Key words: Echinococcus multilocularis, Immune-related molecule, Host-parasite interplay