›› 1997, Vol. 15 ›› Issue (6): 362-365.

• 论著 • Previous Articles     Next Articles

NTIGENIC SIMILARITY BETWEEN SCHISTOSOMA JAPONICUM EGG AND TRICHINELLA SPIRALIS MUSCLE LARVA ANTIGEN

Zeng Qingren1; Lu Yuyun2; Yi Xinyuan1; Zeng Xianfang1; Wang Shiping1; Peng Xianchu1   

  1. 1 Departm ent of Parasitology; H unan Medical University; Changsha 410078 2 Hygienic School of Conghua; Guangdong; Conghua 510900
  • Received:1900-01-01 Revised:1900-01-01 Online:1997-12-28 Published:1997-12-28

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Abstract: AIM:To analyse the antigenic similarity between Schistosoma japonicum egg and Trichinella
spiralis muscle larva(TsMLA). METHODS:Soluble egg antigen of S.japonicum (Sj EA) and soluble muscle larva antigen of T.spiralis (TsMLA) were analysed by EITB and ELISA techniques. RESULTS:EITB showed that:in TsMLA, the antigens
of 44, 53, 60, 64, 66/70 and 100 kDa were recognized by SjIRS, while 31, 42, 46, 51/53 and 58/60 kDa antigens byα- SjEARS; in SjEA, the antigens of 46, 58 and 64 kDa were recognized by TsIRS, while 58, 60, 64 and 70 kDa proteins by α-T sMLARS. ELISA showed that the levels of antibodies against T. spiralis larva antigens in SjIRS were higher than those of antibodies against S. japonicum egg antigens in TsIRS. CONCLUSION: SjEA and TsMLA shared common antigens mainly among 44-70 kDa, but there were also differences in antigenic similarity between both S.japonicum egg and T.spiralis muscle larva.

Key words: Schistosoma japonicum, Trichinella spiralis, comm on antigen, EITB