Laboratory diagnosis of two misdiagnosed imported Plasmodium ovale malaria cases in Shanghai

doi:10.12140/j.issn.1000-7423.2021.04.022

Abstract

Abstract:

Laboratory diagnosis was performed using microscopic examination, rapid malaria diagnostic test (RDT) and malaria nucleic acid test (NP-2002 method, multiplex PCR method and qPCR method) on two blood samples of imported malaria patients, to which there was controversy on the Plasmodium species. The initial examination of case 1 in a district-level center for disease control and prevention (CDC) in region A found P. falciparum (Pf) by microscopy, and Pf by RDT, whereas nucleic acid test was not done. The examination result was rechecked by Shanghai Municipal Center for Disease Control and Prevention (SCDC), presenting confirmation of P. ovale (Po) by microscopy, Pf by RDT, and Po by nucleic acid detection. The initial examination results of case 2 using microscopy, RDT, and nucleic acid detection in the district B CDC all revealed P. vivax (Pv). The recheck results of SCDC were Po by microscopy, negative finding by RDT, and Po by nucleic acid detection.

Key words: Imported malaria, Plasmodium ovale, Microscopic examination, Rapid malaria diagnostic test, Nucleic acid test

CLC Number:

R531.3

ZHANG Yao-guang, JIANG Li, WANG Zhen-yu, ZHU Min, ZHU Qian, MA Xiao-Jiang, WU Huan-yu. Laboratory diagnosis of two misdiagnosed imported Plasmodium ovale malaria cases in Shanghai[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2021, 39(4): 553-556.

Figures/Tables 4

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