中国寄生虫学与寄生虫病杂志 ›› 2006, Vol. 24 ›› Issue (1): 16-26.

• 研究简报 • 上一篇    下一篇

复方蒿甲醚及复方甲氟喹治疗恶性疟56例

沈文娟1;Moulaye Thiero 2   

  1. 1 浙江省嘉兴市第一医院儿科,嘉兴314000;2 马里共和国Markala医院 Markala
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2006-02-28 发布日期:2006-02-28

Coartem and Fansimef in the Treatment of Falciparum Malaria

SHEN Wen-juan1;Moulaye Thiero2   

  1. 1 Department of Pediatrics,The First Hospital of Jiaxing,Jiaxing 314000,China; 2 Department of Pediatrics,Markala Hospital,the Republic of Mali
  • Received:1900-01-01 Revised:1900-01-01 Online:2006-02-28 Published:2006-02-28

摘要: 2001~2003年,作者在西非马里采用WHO推荐的复方蒿甲醚及复方甲氟喹治疗方案,治疗4~14岁恶性疟各28例。平均退热时间、无性体阴转时间及治愈率,复方蒿甲醚组分别为(35.3±6.4)h、(34.7±6.9)h及100%,复方甲氟喹组分别为(32.6±5.8)h、(36.8±5.3)h及96.4%。两组间差异均无显著性(P>0.05)。

关键词: 复方蒿甲醚, 复方甲氟喹, 恶性疟, 药物治疗

Abstract: From 2001 to 2003, anti-malarial combination coartem and fansimef, recommended by WHO, were used to treat falciparum malaria in Mali, 28 cases in each group. The mean fever clearance time, mean asexual parasite clearance time and the cure rate in 28 days were 35.3±6.4, 34.7±6.9 hours and 100% respectively in coartem group, and 32.6±5.8, 36.8±5.3 hours and 96.4% respectively in the fansimef group, with no significant difference between the two groups (P>0.05).

Key words: Coartem, Fansimef, Falciparum malaria, Therapy