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The Role of Dendritic Cells in Host Immunity against Helminth Infections

JIANG Jing1,2,ZHAO Quan2,YANG Gui-lian1 *   

  1. College of Animal Science and Technology,Jilin Agricultural University;Jilin Provincial Engineering Research Center of Animal Proboscis,Changchun 130118,China;2 College of Animal Science and Technology,Changchun University of Science and Technology,Changchun 130600,China
  • Online:2015-04-30 Published:2015-05-04

Abstract:

 Dendritic cells are the strongest professional antigen-presenting cells. Helminth infection could promote maturation of immature dendritic cells, induce Th2-type immune responses, and inhibit the normal function of dendritic cells which is closely associated with the immune evasion. This paper reviews the role of dendritic cells in host immunity against helminth infections.

Key words: Dendritic cell, Helminth, Immunoregulation, Toll like receptor