Controlled Veterinary Drug Delivery Systems against Parasitic Infection

Abstract

Abstract:

Parasitic infections， especially the gastrointestinal and lung nematode infections， are most common in livestock in temperate areas， and it is the major constraints affecting livestock production. In grazing season， outdoor activities of animals cause inconvenience to the application of antiparasitic drugs. Therefore， controlled drug delivery systems can prolong the effect time and reduce the difficulty of drug administration. This review summarizes several types of long-term delivery devices and dosage forms including intraruminal devices， long-acting injectables， in-situ forming implants， novel microparticles and nanoparticles. Their advantages and drawbacks are dicussed.

Key words: Controlled drug release, Parasite, Intraruminal device, Long-acting injectable, In situ forming implant, Microparticle, Nanoparticle

TU Zhen，ZHANG Hao-bing*. Controlled Veterinary Drug Delivery Systems against Parasitic Infection[J]. .

[1]	YANG Yang, WANG Xu, LI Mengqing, XUE Chuizhao, ZUO Qingqiu, YIN Jianhai, CAO Jianping. Species composition, host specificity and genetic diversity of ectoparasites on rodents in Shiqu County, Sichuan Province [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2026, 44(1): 94-101.
[2]	QIN Ruofang, XU Haiping, XU Yijiong, DAI Simin, LV Shan, CUI Yan. Surveillance of foodborne parasite in market-sold food in Putuo District, Shanghai Municipality from 2017 to 2024 [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2025, 43(5): 690-696.
[3]	XU Xiaojuan, CHEN Xuefeng, WU Fan, WU Chenyang, LIU Ting, DAI Bo, ZHANG Shiqing. Prevalence of intestinal parasitic infection in wild mice along the Yangtze River basins in Anhui Province in 2022 [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2025, 43(5): 727-730.
[4]	WANG Xu, YIN Jianhai, HAN Shuai, YANG Yang, LI Mengqing, SHEN Yujuan, CAO Jianping. Health threat and ecological function of parasites [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2025, 43(4): 463-468.
[5]	CHEN Meng, TAO Hong, LI Yanzhong, ZHANG Juan, ZHOU Xiaomei. Investigation of intestinal parasitic infections among the population in areas inhabited by Bulang nationality in Yunnan Province [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2024, 42(5): 623-628.
[6]	XU Kai, CHEN Li, LIN Dengfeng. Advances in the treatment of inflammatory bowel disease with parasites and their agents [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2024, 42(3): 407-412.
[7]	MA Yue, ZHAO Baocai, ZHOU Jiali, HU Junhao, ZHAO Hongxi. Research progress on the regulation of miRNA in the infection of apicomplexan parasites [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2023, 41(6): 749-755.
[8]	YANG Jinting, HUANG Xiaobin, WANG Yujuan, GUO Xianguo, ZHANG Xianzheng, YANG Huijuan, ZHENG Xiaoyan. Myotis fimbriatus ectoparasite infection and the morphological and phylogenetic analysis of Nycteribiidae in Dali, Yunnan Province [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2023, 41(4): 452-458.
[9]	WANG Feng, WU Fan, LI Linlin, HUANG Qingqing. Prevalence of parasitic infections in wild mice in Wuhu City, Anhui Province [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2023, 41(4): 516-519.
[10]	WU Xiaoying, HU Yuan, CAO Jianping. Preparation of Echinococcus granulosus peptide embedded in chitosan quaternary ammonium salt nanoparticles [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2023, 41(3): 300-305.
[11]	XIE Yi, WANG Ying, WANG Xu, SHI Dandan, FU Meihua, LI Chunyang, WU Weiping, DAN Bazeli, LIAO Sa, ZHANG Kaige, DENG Xueying, GUAN Yayi. Investigation of fecal parasite pathogens in domestic dogs based on high-throughput sequencing [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2023, 41(3): 325-330.
[12]	RONG Zhi-li, SHI Ting-ting. A misdiagnosed case of brain sparganosis mansoni [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2022, 40(6): 817-820.
[13]	XU Zhi-peng, JI Min-jun, WU Guan-ling. The toxicological and pharmacological effects of parasite-derived components on the host [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2022, 40(5): 561-571.
[14]	LI Mei, ZHOU He-jun, YIN Jian-hai, ZHANG Li, TU Hong. Investigation on parasite density and treatment measures in malaria patients [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2022, 40(3): 379-383.
[15]	PAN Xiao-wen, WU Yin-juan, HE Qing, YIN Ying-xuan, LI Xue-rong. Research advances on exosome and its functions to parasitic helminths [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2022, 40(3): 390-395.

Controlled Veterinary Drug Delivery Systems against Parasitic Infection

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments