Influence of nutritional metabolism of Anopheles on its transmission capability of malaria parasites

doi:10.12140/j.issn.1000-7423.2021.05.009

Abstract

Abstract:

Nutritional metabolism of mosquitoes provides a variety of nutrients and signaling molecules to ensure their growth, development and reproduction. At the same time, malaria parasites utilize Anopheles’ nutritional metabolism for acquisition of nutrients to ensure their own development and proliferation. Up to now, little is known regarding the impact of malaria parasite invasion on Anopheles host metabolism, and how mosquito metabolism affects itself reproduction, immune response and other physiological changes during pathogenic invasion. This review summarizes the interplay between Anopheles metabolism and malaria parasite from the aspects of metabolism of glucose, lipids and amino acids, to provide clues for development of mosquito-borne infectious diseases.

Key words: Anopheles, Malaria parasites, Metabolism

CLC Number:

R384.111

SONG Xiu-mei, WANG Jing-wen. Influence of nutritional metabolism of Anopheles on its transmission capability of malaria parasites[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2021, 39(5): 617-620.

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