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Research Progress on the Molecular Mechanisms of Mosquito Innate Immunity

GUO Xiu-xia，WANG Huai-wei *   

  1. Shandong Institute of Parasitic Diseases；Shandong Academy of Medical Sciences；Key Laboratory of Medicine and Health in Shandong Province，Jining 272033，China
  • Online:2015-02-28 Published:2015-05-04
  • Supported by:

    Supported by a project of Shandong Academy of Medical Sciences（No. 2013-39）and the National Natural Science Foundation of China（No. 81271877, 81201318）

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Abstract:

As the important vector of the mosquito-borne diseases， mosquitos rely on their innate immune system against pathogens infection， which includes cellular immunity and humoral immunity. Both of them are interacted and coordinated， via the pattern recognition receptors， immune signaling， antimicrobial peptides， phenoloxidase-based melanization， phagocytosis， and so on. This paper reviews the research progress on the molecular mechanisms of mosquito innate immunity.

Key words: Mosquito, Innate immunity, Molecular mechanism