›› 1998, Vol. 16 ›› Issue (1): 2-10.

• 论著 • Previous Articles     Next Articles

RESEARCHES ON IMMUNOGENICITY IDENTIFICATION OF RECOMBINANT Sj 22.6(r Sj 22.6) kDa ANTIGEN GENE OF SCHISTOSOMA JAPONICUM 

ang Guiyun ; Zhang Zhaosong; Chen Shuzhen; Shen Yiping; Wu Haiwei; Su Chuan; Wu Guanling   

  1. Department of Parasitology; Nanjing Medical University; Nanjing 210029;
  • Received:1900-01-01 Revised:1900-01-01 Online:1998-02-28 Published:1998-02-28

Abstract: AIM:To identify the immunogenicity and the potentiality of r Sj 22.6 as a candidate vaccine antigen for schistosomiasis japonica. METHODS:r Sj 22.6 was tested by Western blot with specific antibodies to identify its immunogenicity.The r Sj 22.6 protein was isolated and purified by SDS PAGE and injected twice into rabbits to raise antir Sj 22.6 serum that was tested by Western blot to recognize the native protein of adult S.japonicum and SEA.C57 mice were immunized with r Sj 2...

Key words: Schistosoma japonicum, rSj 22.6, recombinant antigen, immunogenicity