Research progress on liver fibrosis caused by Echinococcus infection

doi:10.12140/j.issn.1000-7423.2022.05.014

Abstract

Abstract:

Echinococcus infection may cause damage to hepatocytes. Hepatic fibrosis is a process of excessive proliferation of connective tissue after liver injury. In the dynamic process of liver self-healing, the activation of hepatic stellate cells, the increased extracellular matrix production and the decreased extracellular matrix consumption result in fibrosis. This review summarizes the regulatory mechanisms of hepatic stellate cells, cytokines and microRNA involved in hepatic fibrosis caused by Echinococcus infection.

Key words: Echinococcus, Hepatic fibrosis, Cytokines, MicroRNA

CLC Number:

R532.32

JIANG Xiao-feng, SHEN Yu-juan. Research progress on liver fibrosis caused by Echinococcus infection[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2022, 40(5): 656-660.

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