CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES ›› 2021, Vol. 39 ›› Issue (4): 429-436.doi: 10.12140/j.issn.1000-7423.2021.04.002

• INVITED REVIEW • Previous Articles     Next Articles

New progress in basic and clinical research of advanced schistosomiasis

LIU Rong(), WEN Li-yong*()   

  1. Hangzhou Medical University, Zhejiang Provincial Center for Schistosomiasis Control, Hangzhou 310013, China
  • Received:2021-06-21 Revised:2021-07-08 Online:2021-08-30 Published:2021-08-12
  • Contact: WEN Li-yong E-mail:liurong273101@163.com;wenliyong@126.com
  • Supported by:
    Major Projects of National Social Science Foundation of China(16ZDA237)

Abstract:

At present, the endemic situation of schistosomiasis is at the lowest level in history in China, and the infection rate has decreased significantly, but there are still a large number of patients with advanced schistosomiasis. Advanced schistosomiasis is the most serious type of schistosomiasis, which seriously endangers the health and quality of life of patients. Liver granuloma and fibrosis caused by Schistosoma eggs are the leading cause for the death of advanced schistosomiasis patients. This article summarizes the pathological mechanism, determine approaches, treatment and prognosis of liver fibrosis in basic and clinical research of advanced schistosomiasis, hoping to provide reference information for future schistosomiasis prevention and treatment.

Key words: Schistosomiasis, Advanced, Hepatic fibrosis, Basic, Clinical

CLC Number: