Advances in research of structure, function and regulatory mechanism of Toxoplasma gondii conoid

doi:10.12140/j.issn.1000-7423.2021.06.016

Abstract

Abstract:

The apical complex is the typical structure of phylum Apicomplexa which consists secretory organelles and cytoskeletal elements, of which a marked feature is the conoid formed by tubulin fibers. Toxoplasma gondii has a relatively intact conoid, thus, it provides a successful model for analyzing the structure, composition and function of conoid. The stability and relevant activities of conoid are closely related to gliding motility and microneme secretion in of Toxoplasma, and are critical for host cell invasion. In this paper, the structure stability, protein function and regulatory mechanism of conoid are reviewed.

Key words: Toxoplasma gondii, Conoid, Gliding motility, Invasion, Calcium regulation

CLC Number:

R382.5

ZHANG Xiao-han, FENG Ying, CHEN Ran, SANG Xiao-yu, YANG Na. Advances in research of structure, function and regulatory mechanism of Toxoplasma gondii conoid[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2021, 39(6): 832-835.

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