miRNA functions in parasite-related immune regulation in hosts

Abstract

Abstract:

MicroRNAs (miRNAs) are endogenous small-molecule RNAs that participate in the regulation of physiological and pathological processes through post-transcriptional regulation of gene expression. Exploring the functions of miRNAs in host-parasite interactions has become a research focus these years, with topics including the transmission of miRNAs from parasites, the miRNA-mediated regulation of host immune responses, the intermediate host responses, and the immunopathological effects induced by parasite infection. In this review we summarize the latest studies on these topics in order to provide new insights for further research on pathogenesis mechanisms of the parasites.

Key words: Parasite, miRNA, Immune regulation

CLC Number:

Ke LIU, Hai-bin HUANG, Gui-lian YANG. miRNA functions in parasite-related immune regulation in hosts[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2018, 36(4): 405-408.

References 43

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