›› 2012, Vol. 30 ›› Issue (3): 13-196-200.

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Research Advances of Interleukin-15 in Anti-parasitic Infection

LI Jia-yuan1,2, LI Zhong-yuan1,2, WANG Yan1,2, ZHU Xing-quan1, XU Min-Jun1 *   

  1. 1 State Key Laboratory of Veterinary Etiological Biology,Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute,CAAS,Lanzhou,730046,China; 2 College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642,China
  • Online:2012-06-30 Published:2012-09-28

Abstract: Interleukin-15(IL-15) is a pro-inflammatory cytokine and also a chemotactic factor for a variety of immune cells, which participates in and regulates the inflammatory response and immune response to organisms. Up to now, the molecular structure and receptor of IL-15 have been widely researched, with important advances in its signal transduction way. However, its application in parasitology is still a relatively new topic. This article summarizes the latest research development of IL-15 in anti-parasitic infection, prospects its mechanism and application.

Key words: Interleukin-15 (IL-15), Anti-parasitic immunity, Helminth, Protozoan