›› 2010, Vol. 28 ›› Issue (4): 17-267.

• 研究简报 • Previous Articles     Next Articles

Genotyping of Plasmodium vivax in China-Myanmar Border by Circumsporozoite Protein

XU Gui-Quan1，ZHANG Zai-xing2 *，LI Na3，DAI Hong-jian4   

  1. 1 The Fourth People's Hospital of Guiyang，Guizhou 550002，China；2 Yunnan Institute of Parasitic Diseases，Simao 665000，China；3 HuaXi Public Health Institute，Sichuan University，Chengdu 610041，China；4 Kunming Children’s Hospital，Kunming 650034，China
  • Received:1900-01-01 Revised:1900-01-01 Online:2010-08-30 Published:2010-08-30

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Abstract: By using a series of type-specific primers for Plasmodium vivax circumsporozoite protein （CSP） gene and nested PCR, genotyping was conducted for the specimens of Plasmodium vivax isolated from China-Myanmar border. In 174 isolates of P. vivax, four genotypes, namely, tropical zone family strain, temperate zone family strain, genotype-mixed infection and PV-II type, were identified each accounting for 54.6 %, 35.6%, 6.9%, and 2.9%, respectively. The tropical zone family strain was dominant in the border area. There was no significant difference on the P.v CSP genotype constitution between Laza isolate of Myanmar and Tengchong isolate of Yunnan, China

Key words: Plasmodium vivax, Circumsporozoite protein, Genotyping