›› 2007, Vol. 25 ›› Issue (2): 15-149.

• 现场研究 • Previous Articles     Next Articles

Observation on the Change of Anti-S.japonicum Antibody Level inPopulation Migrated from Outside Embankment to New Town

WEN Li-yong1;LU Shao-hong1;CHEN Jun-hu1;ZHANG Jian-feng1;YU Li-ling1;DING Jian-zu1;YAN Xiao-lan1;SHEN Li-ying1;ZHENG Wei2;GAO Lu-lu2;WANG Tian-ping3;ZHANG Shi-qing3;CHEN Geng-xin4;YE Yun5;ZHOU Xiao-nong6;ZHENG Jiang6   

  1. 1 Institute of Parasitic Diseases, Zhejiang Academy of Medical Sciences, WHO Collaborating Center for Research on Helminthiasis, Hangzhou 310013, China; 2 Department of Disease Control, Health Bureau of Zhejiang Province, Hangzhou 310006, China; 3 Anhui Institute of Parasitic Diseases, Wuhu 241000, China; 4 Guichi District Station of Schistosomiasis Control, Guichi 247100, China; 5 Dongzhi County Station of Schistosomiasis Control, Dongzhi 247200, China; 6 Institute of Parasitic Diseases, National Center for Disease Prevention and Control, Shanghai 200025, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2007-04-30 Published:2007-04-30
  • Contact: WEN Li-yong1

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Abstract: Objective To detect the change of the anti-S.japonicum antibody level after people migrated from outside embankment to newly established town. Methods Three pilot spots were established for the investigation: one spot that both inhabitancy and cultivation disused （A）, one spot that only inhabitancy disused but farming continued （B） and the third one served as control （C）. DIGFA and ELISA were used to detect the antibody level in the populations from 2002 to 2005. Results The positive rate of anti-S. japonicum antibody declined significantly from 6.63% to 3.52% by DIGFA and from 7.26% to 3.71% by ELISA at spot A （χ2=5.2625， P<0.05； χ2=6.3296， P<0.05, respectively）. There was no significant difference on the positive rate of antibody in spots B and C. The average A450 value of ELISA in the three spots was statistically analyzed by One-Way ANOVA. It was only in spot B that the average A450 value declined from 0.182 in 2003 to 0.147 in 2005 （P<0.01）. Conclusion The anti-S.japonicum antibody level in human population has decreased at certain degree after they migrated from outside embankment to new town.

Key words: Migration, Schistosoma japonicum, Antibody