›› 1998, Vol. 16 ›› Issue (6): 460-462.

• 防治经验 • Previous Articles     Next Articles

IN VITRO SENSITIVITY OF PLASMODIUM FALCIPARUM TO CHLOROQUINE,PIPERAQUINE,PYRONARIDINE AND ARTESUNATE IN YUXI PREFECTURE OF YUNNAN PROVINCE

Fan Bo 1; Zhao Wei 1; Ma Xinwen 2; Huang Zhengmei 1; Wen Yunsheng 2; Yang Jiqing 2;
Yang Zongxiang 2   

  1. 1 Yuxi City Health and Antiepidemic Station; Yuxi 653100 2 Yuanjiang County Health and Antiepidemic Station; Yuanjiang 653300
  • Received:1900-01-01 Revised:1900-01-01 Online:1998-12-31 Published:1998-12-31

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Abstract: AIM:To assess the sensitivity of Plasmodium falciparum to four antimalarials.
METHODS:WHO standard in vitro microtest was used.RESULTS: The resistance rates of the malaria
parasite to chloroquine,piperaquine pyronaridine and artesunate were 85 7%, 66 7%, 38 1% and 5
0%,respectively. CONCLUSION: Among the antimalarials tested in Yuxi Prefecture,Yunnan
Province,high resistance of P.falciparum to chloroquine and piperaquine was found.The
sensitivity of P.falciparum in part of the case to pyronaridine decreased. However, most of the cases were relatively sensitive to artesunate.

Key words: Plasmodium falciparum, in vitro microtest, chloroquine, piperaquine, pyronaridine, artesunate