An overview on the resistance of Plasmodium falciparum to primary anti-malarial drugs in China

doi:10.12140/j.issn.1000-7423.2020.05.016

Abstract

Abstract:

Malaria is prevalent in tropical and subtropical regions, and is one of the public health problems in Africa and Southeast Asia. Although since 2017 there has been no indigenous malaria cases reported in China, it is still of particular importance to treat and care imported falciparum malaria cases, monitor anti-malarial drugs, and prevent the occurrence or outbreak of local cases caused by imported cases. The anti-malarial drugs have long been one of the main approaches for malaria control and have effectively controlled the global transmission of malaria. However, with the long-term use of anti-malarial drugs, the problem of drug resistance of P. falciparum, particularly the resistance to artemisinin drugs, has become one of the major challenges for malaria prevention and control at present. In this review, we summarize the researches on the resistance of P. falciparum to some main anti-malarial drugs in China.

Key words: Plasmodium falciparum, Resistance to anti-malarial drug, Artemisinin drugs

CLC Number:

R382.312

YE Sheng-yu, CHENG Yi-yi, LI Man, ZHOU Hong-ning. An overview on the resistance of Plasmodium falciparum to primary anti-malarial drugs in China[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2020, 38(5): 631-636.

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