Abstract: 【Abstract】 Sixteen AIDS patients complicated with toxoplasmic encephalitis （TE） were retrospectively analyzed between August 2008 to August 2009 with a mean age of （37.0±11.6） years. The most common clinical symptoms were headache （68.8%, 11/16） and fever （62.5%, 10/16）, and 6 with Babinski sign （37.5%）. 81.3%（13/16）were with CD4+ cells＜200/mm3. Both sera and CSF showed 62.5% （10/16） TOXO-IgG positive by ELISA. CT and MRI scan demonstrated bilateral and multiple lesions with marked peripheral edema effect, and an enhanced scanning showed small finger ring as the major feature. 15 patients got improved by either oral sulphadiazine tablets or sulphadiazine tablets plus clindamycin capsule, 10 cases received combined HAART treatment, and 1 case died with septic shock.

Key words: AIDS, Toxoplasmic encephalitis, Opportunistic infection, Clinical analysis, Therapy