Research progress on pathogens carried by sand flies and their gut microbiota

doi:10.12140/j.issn.1000-7423.2025.01.020

Abstract

Abstract:

As a vector of multiple pathogens, sand flies have important epidemiological significance. A large number of microbial communities are colonized in the gut of sand flies, which pose a significant impact on the reproduction, growth and development of sand flies and sand flies-borne pathogens. The review summarizes the species of pathogens carried by sand flies and the composition of gut microbiota, and unravel the interactions among sand flies, pathogens, and gut microbiota. Gut microbiota not only directly inhibits the infection and transmission of pathogens, but also indirectly alters the ability of pathogen infections and transmission by sand flies through participation in the immune responses and defense mechanisms of sand flies.

Key words: Sand fly, Pathogen, Gut microbiota

CLC Number:

R384.1

CUI Lei, FANG Yuan, ZHOU Zhengbin, HE Yaqi, ZHANG Yi. Research progress on pathogens carried by sand flies and their gut microbiota[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2025, 43(1): 129-134.

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