Research progress on vascular invasion of hepatic alveolar echinococcosis

doi:10.12140/j.issn.1000-7423.2022.04.016

Abstract

Abstract:

The surgical treatment for multilocular hepatic echinococcosis is determined by the severity of the lesion invasion to the important vascular system (blood vessels, bile ducts and lymph nodes). Currently, the clinical relationships among the pathological changes, examination indications and treatments of vascular invasion, bile duct invasion and lymph node metastasis are not clear. Here we have summarized recent advances worldwide in multilocular hepatic echinococcosis. The mechanisms of multilocular hepatic echinococcosis progression and metastasis, the pathological distribution of the lesions and the clinical imaging, the morphology and microscopic characteristics of the vascular invasion were reviewed. This review will shed light on the development and research of the diagnosis and treatment of vascular invasion caused by multilocular hepatic echinococcosis.

Key words: Hepatic alveolar echinococcosis, Vascular system, Invasion

CLC Number:

R532.32

ZHANG Ting-ting, DU Qiu-pei, GUO Xin-jian, ZHANG Ling-qiang, WANG Zhi-xin, CHANG Zheng-song, ZHAO Qian, WANG Hai-jiu, HOU Li-zhao. Research progress on vascular invasion of hepatic alveolar echinococcosis[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2022, 40(4): 516-523.

Figures/Tables 13

References 37

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分区	分层	特点
Ⅰ区：病灶	a：角皮层	类同心圆叠层的粉皮,无细胞结构
	第1层：坏死区	角皮层周围广泛的无结构坏死区
Ⅱ区：边缘带/ 浸润带/ 炎症反应带	第2层：内环	不规则,由上皮样细胞和中性粒细胞形成
Ⅱ区：边缘带/ 浸润带/ 炎症反应带	第3a层：内纤维环	长条形纤维化区域,由纤维胶质形成
	第4层：外环	炎症细胞带区,由大量淋巴细胞、嗜酸粒细胞、巨噬细胞、中性粒细胞、浆细胞等炎症细胞及少量反应组织细胞组成（图4-B^[10]）
	第3b层：外纤维环	额外的纤维性边缘,可见淋巴细胞浸润,部分可无该层
Ⅲ区：正常肝组织	第5层：周围肝组织	邻近肝组织,肝细胞气球样变,周围纤维组织增生、淤血、胆汁瘀滞,汇管区炎症细胞浸润