Research progress on calcium-binding protein in Toxoplasma gondii

Abstract

Abstract:

Toxoplasma gondii, a type of apicomplexa protozoan parasite, can infect nucleated cells. Studies have shown that Ca²⁺ is associated with physiological activity of Toxoplasma gondii such as infection and movement. Ca²⁺ is abundant in endoplasmic reticulum. There are many calcium-binding proteins important for physiological activity of Toxoplasma gondii. The calcium-binding proteins contain various EF-hand （EF） motifs, and currently there are 55 such proteins according to the records in Toxo DB, and 69 in Plasmo DB. In this review, the roles of Ca²⁺-binding proteins are discussed.

Key words: Toxoplasma gondii, Apicomplexa, Calcium-binding protein

CLC Number:

R383.3

Xu ZHAO, Ting ZHANG, Yi-wei ZHANG, Da-wei WANG, Ying FENG, Na YANG, Ran CHEN, Xiao-yu SANG, Qi-jun CHEN, Ning JIANG. Research progress on calcium-binding protein in Toxoplasma gondii[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2018, 36(5): 525-528.

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