Serological survey on hydatid disease in children of 6-12 years in the northern region of Xinjiang Uygur Autonomous Region

Abstract

Abstract: Objective To understand the epidemiological situation of hydatid disease in children aged 6-12 years in the northern region of Xinjiang Uygur Autonomous Region. Methods Children aged 6 to 12 years in 200 primary schools selected by stratified sampling were made in 9 regions/states/municipalities (Ili Kazak Autonomous Prefecture, Bortala Mongolia Autonomous Prefecture, Tacheng, Altay, Karamay, Changji Hui Autonomous Prefecture, Urumqi, Turpan and Hami) in northern Xinjiang from August 2012 to September 2013. The serum level of anti-echinococcus IgG were determined by ELISA. Data were analyzed with χ² test. Results A total of 89 006 children were examined, and 1 956(2.20%) were positive for anti-echinococcus IgG. Among the sites of survey, the positive rate was highest in Tacheng (3.91%, 510/13 027), and lowest in Turpan (0.56%, 32/5 765) (χ² = 161.06, P < 0.05). The positive rate in males was 3.12% (998/47 006) and that in females was 2.23% (958/42 000). Among different age groups, the positive rate was highest in the group of 12 years (2.38%, 505/21 178) and lowest in 10 year group (2.10%, 306/14 594) (χ² = 3.23, P > 0.05). There was no significant difference among the age groups (χ² = 0-3.23, P > 0.05). Children of Kazakh, Mongolian, Hui, Han, and Uygur nationalities accounted for 99.23% (88 497/89 006), with a positive rate of 3.09% (971/31 417), 2.81% (33/1 176), 1.82% (174/9 564), 1.70% (559/32 965) and 1.58% (211/13 373), respectively. The positive rates in children of Kazak and Mongolian ethnicities were significantly higher than those of Hui, Han and Uygur ethnicities (χ² = 5.37-9.89, P < 0.05). Conclusions There remains a relatively high sera-prevalence of echinococcosis in children of 6 to 12 years in the northern region of Xinjiang, especially in those of Kazak and Mongolian nationalities.

Key words: Echinococcosis, Serosurvey, Children, Northern region of Xinjiang

CLC Number:

R532.32

WUMAIER Maimaitijiang, ASIMU Asiya, Duan-ming WANG, OSMAN Yisilayin, Ning XIAO. Serological survey on hydatid disease in children of 6-12 years in the northern region of Xinjiang Uygur Autonomous Region[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2017, 35(3): 246-249.

Figures/Tables 3

Table 1

Table 2

Table 3

References 24

[1]	Eckert J, Gemmell MA, Meslin FX, et al.人与动物棘球蚴病手册[M]. 伍卫平, 江莉, 韩秀梅, 等. 译. 上海: 文汇出版社, 2014: 26-75.
[2]	Kern P, Bardonnet K, Renner E, et al. European echinococcosis registry: human alveolar echinococcosis, Europe, 1982-2000[J]. Emerging Infect Dis, 2003, 9(3): 343-349.
[3]	余森海. 棘球蚴病防治研究的国际现状和对我们的启示[J]. 中国寄生虫学与寄生虫病杂志, 2008, 26(4): 241-244.
[4]	李炳军, 郭淑霞, 彭心宇. 包虫病流行病学调查现状[J]. 医学综述, 2009, 15(8): 1195-1198.
[5]	蒋次鹏. 棘球绦虫和包虫病[M]. 济南: 山东科学技术出版社, 1994: 1-20.
[6]	伊斯拉音·乌斯曼, 侯岩岩, 赵江山, 等. 2005-2013年新疆棘球蚴病手术病例回顾分析[J]. 中国寄生虫学与寄生虫病杂志, 2014, 32(5): 334-338.
[7]	买买提江·吾买尔, 陈晓英, 伊斯拉音·乌斯曼, 等. 2015年新疆维吾尔自治区人体肠道原虫流行病学调查[J]. 中国寄生虫学与寄生虫病杂志, 2016, 34(4): 361-365.
[8]	魏明远. 新疆三大山系区域包虫病的流行概况[J]. 地方病通报, 1994, 9(2): 78-82.
[9]	傅承, 伊斯拉音·乌斯曼, 焦伟, 等. 新疆额敏县首次发现水感染多房棘球蚴[J]. 地方病通报, 2001, 16(4): 39-40.
[10]	蒋卫, 徐琪毅. 新疆尼勒克县首次发现伊犁田鼠感染多房棘球蚴[J]. 地方病通报, 2000, 15(1): 36-37.
[11]	林宇光, 祁志荣. 新疆塔城地区多房棘球蚴的鼠类宿主考察[J]. 地方病通报, 1993, 8(2): 29-33.
[12]	柴君杰, 蒋卫, 伊斯拉音·乌斯曼, 等. 新疆北部多房棘球绦虫动物宿主研究初报[J]. 中国人兽共患病杂志, 2003, 19(5): 89-91.
[13]	丁木拉提, 郭水忠, 高水盛, 等. 新疆自治区尼勒克县乌拉斯台乡包虫病流行病学调查[J]. 中华流行病学杂志, 2005, 26(2): 131.
[14]	张贺玲, 荆强, 张波, 等. 新疆和静县一例肝泡型包虫病病例报告[J]. 地方病通报, 2000, 15(4): 72
[15]	伊斯拉音·乌斯曼, 童苏祥, 孟贺巴特, 等. 2003年新疆包虫病流行病学调查报告[J]. 地方病通报, 2009, 24(1): 65-67.
[16]	买买提江·吾买尔, 阿迪力·司马义, 伊斯拉音·乌斯曼, 等. 2012年新疆维吾尔自治区人群棘球蚴病流行病学调查[J]. 中国寄生虫学与寄生虫病杂志, 2016, 34(3): 249-254.
[17]	王虎, 曹得萍, 马淑梅, 等. 不同血清学方法对调查现场包虫病人血清的检测及评价[J]. 中国人兽共患病杂志, 2000, 16(6): 67-69.
[18]	中华人民共和国卫生部. 包虫病诊断标准(WS 257-2006)[S]. 北京: 人民卫生出版社, 2006.
[19]	张可久, 韩玲玲, 徐世东, 等. 新疆福海县2001年包虫病防治试点研究报告[J]. 地方病通报, 2003, 18(2): 28-28, 84.
[20]	何鸿超, 关宝齐, 董红艳, 等. 乌鲁木齐县包虫病流行病学调查[J]. 地方病通报, 1998, 13(4): 51-52.
[21]	柴君杰, 焦伟, 伊斯拉音, 等. 新疆北部地区囊型包虫病的流行现状[J]. 热带病与寄生虫学, 2004, 2(3): 139-143.
[22]	吾拉孜汉. 新疆吉木乃县托普铁热克乡人群包虫病血清流行病学调查[J]. 地方病通报, 1995, 10(2): 104, 107.
[23]	柴君杰, 焦伟, 孟贺巴特, 等. 乌鲁木齐南郊农牧区囊型包虫病流行病学研究[J]. 中国病原生物学杂志, 2007, 2(3): 200-203, 227.
[24]	赵江山, 侯岩岩, 张海亭, 等. 新疆南疆地区6~12岁儿童棘球蚴病患病情况调查[J]. 中国寄生虫学与寄生虫病杂志, 2016, 34(4): 370-372, 376.

地区（自治州、市） Prefecture(Autonomous Prefecture)	男性Male			女性Female			合计Total
地区（自治州、市） Prefecture(Autonomous Prefecture)	检查人数No. examined	阳性数 No. positives	阳性率/% Positive rate/%	检查人数No. examined	阳性数 No. positives	阳性率/% Positive rate/%	检查人数No. examined	阳性数 No. positives	阳性率/% Positive rate/%
塔城Tacheng	835	261	3.82	6 192	249	4.02^a	13 027	510	3.91
哈密Kumul	2 843	93	3.27	2 563	115	4.49^a	5 406	208	3.85
阿勒泰Altai	6 716	158	2.35	6 480	167	2.58	13 196	325	2.46
伊犁Ili	9 340	196	2.10	8 352	165	1.98	17 692	361	2.04
博州Bortala	3 146	55	1.75	2 871	52	1.81	6 017	107	1.78
昌吉Sangji	7 220	109	1.51	5 652	106	1.88	12 872	215	1.67
克拉玛依Karamay	708	8	1.13	631	12	1.90	1 339	20	1.49
乌鲁木齐Urumqi	7 254	97	1.34	6 438	81	1.26	13 692	178	1.30
吐鲁番Turpan	2 944	21	0.71	2 821	11	0.39	5 765	32	0.56
合计Total	47 006	998	2.12	42 000	958	2.28	89 006	1 956	2.20

年龄组/岁 Age group/Year	男性Male			女性Female			合计Total
年龄组/岁 Age group/Year	检查人数No. examined	阳性数 No. positives	阳性率/% Positive rate/%	检查人数No. examined	阳性数 No. positives	阳性率/% Positive rate/%	检查人数No. examined	阳性数 No. positives	阳性率/% Positive rate/%
6	1 287	27	2.10	1 261	31	2.46	2 548	58	2.28
7	4 600	99	2.15	4 269	90	2.11	8 869	189	2.13
8	6 309	134	2.12	5 678	121	2.13	11 987	255	2.13
9	6 803	150	2.20	6 299	126	2.00	13 102	276	2.11
10	7 640	149	1.95	6 954	157	2.26	14 594	307	2.10
11	8 965	184	2.05	7 763	183	2.36	16 728	367	2.19
12	11 402	254	2.23	9 776	251	2.57	21 178	505	2.38
合计Total	47 006	998	2.12	42 000	958	2.28	89 006	1956	2.20

民族Nation	男性Male			女性Female			合计Total
民族Nation	检查人数No. examined	阳性数 No. positives	阳性率/% Positive rate/%	检查人数No. examined	阳性数 No. positives	阳性率/% Positive rate/%	检查人数No. examined	阳性数 No. positives	阳性率/% Positive rate/%
哈萨克族Kazak	16 492	483	2.93	14 925	488	3.27	31 417	971	3.09^a
蒙古族Mongolian	599	12	2.00	577	21	3.64	1 176	33	2.81^b
回族Hui	4 965	89	1.79	4 599	85	1.85	9 564	174	1.82
汉族Han	17 796	301	1.69	15 169	258	1.70	32 965	559	1.70
维吾尔族Uyghur	6 878	107	1.56	6 495	104	1.60	13 373	211	1.58
其他民族Other nation	267	6	2.25	244	2	0.82	511	8	1.57
合计Total	46 997	998	2.12	42 009	958	2.28	89 006	1 956	2.20