›› 2014, Vol. 32 ›› Issue (2): 12-143-147.

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Progress of CD8+ T Cell-Mediated Immune Response to Toxoplasma gondii Infection

WU Bin, LYU Fang-li *   

  1. Department of Parasitology, Zhongshan School of Medicine, Sun Yat-sen University; Key Laboratory of Tropical Disease Control, Ministry of Education, Guangzhou 510080, China
  • Online:2014-04-30 Published:2014-07-03

Abstract: Toxoplasma gondii is an obligate intracellular protozoan parasite, which infects warm-blooded animals including humans. T. gondii infection in the immune-competent individual is largely asymptomatic, but it can cause severe toxoplasmosis in immune-deficiency patients. T cell-mediated immunity plays an important role in resistance against T. gondii. Therefore, this review focuses on the progress of CD8+ T cell-mediated immune response to T. gondii infection.

Key words: Toxoplasma gondii infection, CD8+ T cell, Immune response