CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES ›› 2019, Vol. 37 ›› Issue (4): 388-394.doi: 10.12140/j.issn.1000-7423.2019.04.003

• INVUTED REPORTS • Previous Articles     Next Articles

Establishment and innovative practice of Integrative System of Prevention, Diagnosis and Management for echinococcosis in China

Aini ABUDUSALAMU1,2(), Ying-mei SHAO2,3, Aji TUERGANAILI2,3, Wen-bao ZHANG4, Ren-yong LIN4, Yan-yan HOU5, Zhuang-zhi ZHANG6, Hao WEN1,*()   

  1. 1 State Key Laboratory of Pathogenesis, Prevention and Management of High Incidence Diseases in Central Asia, Xinjiang Medical University, Urumqi 830011, China
    2 Department of Hepatobiliary and Hydatid Disease,Urumqi 830011, China
    3 Digestive and Vascular Surgery Center,Urumqi 830011, China
    4 Clinical Medical Institute, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China
    5 Xinjiang Uyghur Autonomous Region Center for Disease Prevention and Control, Urumqi 830001, China
    6 Veterinary Institute, Xinjiang Academy of Animal Sciences, Urumqi 830011, China
  • Received:2019-07-18 Online:2019-08-30 Published:2019-09-05
  • Contact: Hao WEN E-mail:abdusallam925@hotmail.com;dr.wenhao@163.com
  • Supported by:
    Supported by Xinjiang Uyghur Autonomous Region Key Laboratory Open Research Program (No. 2017D04004, No. 2019D04021)

Abstract:

Echinococcosis (hydatid disease) is a neglected tropical zoonotic disease caused by the infection of Echinococcus larvae. It prevails globally and China has the highest disease burden of two main types of echinococcosis including cystic echinococcosis (CE) and alveolar echinococcosis (AE). The hydatid disease is a big threat of public health and a heavy burden of economic lose in China. The AE cases in western China account for over 90% of the total AE cases in the world. Great achievements have been made in the control and treatment of the diseases since the founding of People’s Republic of China, including remarkable improvement in clinical cure rate, significant reduction in morbidity and mortality in humans and infections in animals. China has made inspiring achievements in the research of the genomics, molecular epidemiology, immunology, diagnostic tools, treatment approaches, prevention strategies and vaccine development of echinococcosis especially since the beginning of the 21th century. This paper mainly described and discussed the establishment and innovative practice of Integrative System of Prevention, Diagnosis and Management for echinococcosis in China, which includes systems for scientific prevention and control, standardized diagnosis, innovative surgery and treatment, and relevant research and translational application.

Key words: Echinococcosis, Scientific prevention, Standardized diagnosis, Innovative surgery, Medication, Research and translation

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