中国寄生虫学与寄生虫病杂志 ›› 2011, Vol. 29 ›› Issue (2): 12-138-141.

• 综述 • 上一篇    下一篇

蓝氏贾第鞭毛虫基因表达调控的研究进展

王乙惠,李雅杰*   

  1. 大连大学医学院,大连 116622
  • 出版日期:2011-04-30 发布日期:2012-09-27

Progress on Regulation of Gene Expression in Giardia lamblia

WANG Yi-hui,LI Ya-jie*   

  1. Medical School,Dalian University,Dalian 116622,China
  • Online:2011-04-30 Published:2012-09-27

摘要: 蓝氏贾第鞭毛虫是一种重要的致病性寄生虫,人体感染后主要引起腹泻和营养不良等症状。作为一种源真核生物,其基因表达调控机制可能与其他真核生物有较大的区别。本文从蓝氏贾第虫鞭毛虫启动子、转录因子、转录后调节、翻译起始和表观遗传学等方面,对贾第虫基因表达调控的研究进展进行综述。

关键词: 蓝氏贾第鞭毛虫, 基因表达, 调控

Abstract: Giardia lamblia is an important human pathogen that causes diarrhea and malnutrition. As a late-branching eukaryote, G. lamblia may have special mechanisms for regulating gene expression which differ from other eukaryotes. In this paper, the mechanisms that governing regulation of G. lamblia gene expression, such as promoters, transcription factors, transcriptional regulation, translation initiation and epigenetic mechanisms are summarized.

Key words: Giardia lamblia, Gene Expression, Regulation