miRNA介导血吸虫和宿主相互作用的研究进展

doi:10.12140/j.issn.1000-7423.2020.03.001

摘要/Abstract

摘要：

血吸虫病是一种严重但被忽视的热带传染病,全世界感染血吸虫的人数超过2亿。了解血吸虫和宿主相互作用的机制是有效控制和最终消除血吸虫病的关键。miRNA是一种内源性的非编码小RNA,主要在转录后调控基因的功能。最近,越来越多的证据表明,miRNA是血吸虫和宿主相互作用的关键调控因子。本文综述了miRNA介导血吸虫和宿主相互作用的研究进展。

关键词: 血吸虫, miRNA, 宿主, 相互作用

Abstract:

Schistosomiasis is a serious but neglected tropical infectious disease, with more than 200 million infected people worldwide. A better understanding of the schistosome-host interactions is the key to effectively controlling and ultimately eliminating this disease. miRNA is an endogenous non-coding small RNA, which acts post-transcriptional regulation of gene functions. Recently, growing evidence indicates that miRNA is a crucial regulator of schistosome-host interactions. In this review, we summarize research advances on miRNA-mediated schistosome-host interactions.

Key words: Schistosome, MiRNA, Host, Interaction

中图分类号:

R383.24

何兴, 潘卫庆. miRNA介导血吸虫和宿主相互作用的研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2020, 38(3): 259-262.

HE Xing, PAN Wei-qing. Research progress on miRNA-mediated schistosome-host interactions[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2020, 38(3): 259-262.

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