Abstract: 　AIM: To explore a fast and highly efficient method for the diagnosis of schistosomiasis japonica. METHODS: Using microwave irradiation ELISA(MWI ELISA)and fast ELISA to detect specific antibodies in sera from 118 cases with schistosomiasis japonica, 61 healthy individuals and 12 paragonimiasis cases. RESULTS: The positive rates of schistosomiasis cases were 88 1% (104/118) by MWI ELISA and 91 5% (108/118) by fast ELISA, respectively (χ 2=0 74, P>0 05). The false positive reaction of healthy individuals was found in 2 cases(3 3%) by MWI ELISA and 1 case (1 6%) by fast ELISA, respectively (χ 2=0 34, P>0 05). No false positive reaction was found in paragonimiasis cases. CONCLUSION: The sensitivity and specificity of the two tests were similar, however, MWI ELISA was faster than fast ELISA.

Key words: Schistosomiasis, serological diagnosis, antibody detection, microwave irradiation ELISA