›› 1999, Vol. 17 ›› Issue (2): 16-118.

• 实验研究 • Previous Articles     Next Articles

DETECTON OF CIRCULATING ANTIGEN IN SERA FROM MICE INFECTED WITH TOXOPLASMA TACHYZOITES

JIN Wuguan 1;LI Yunzhu 1;YU Shancang 1;YANG Huizhen 2;QIAN Zongli 2


  

  1. 1 Department of pediatric Medicine;Ruijin Hospital;Shanghai Second Medical University;Shanghai 200025 2 Department of Parasitology;Shanghai Second Medical University;Shanghai 200025
  • Received:1900-01-01 Revised:1900-01-01 Online:1999-04-30 Published:1999-04-30

PDF (PC)

Abstract: 　AIM: To explore an assay method for the early diagnosis of Toxoplasma infection. METHODS: Serum samples collected from three groups of mice infected experimentally with different doses of Toxoplasma trophozoites were detected for the presence of Toxoplasma circulating antigen by using fast ELISA.RESULTS: Toxoplasma circulating antigen was detected on days 4, 4 and 3after infection in light, moderate and heavy infection groups, respectively. CONCLUSION: The level of circulating antigen was in parallel with the duration of infection. The determination of circulating antigen is useful in the early diagnosis of Toxoplasma infection.