Progress researches on Budd-Chiari syndrome and portal hypertension caused by hepatic alveolar echinococcosis

CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES ›› 2026, Vol. 44 ›› Issue (1): 118-123.doi: 10.12140/j.issn.1000-7423.2026.01.017

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Progress researches on Budd-Chiari syndrome and portal hypertension caused by hepatic alveolar echinococcosis

A Jide1()(), CHAI Jinping2, JING Qindong1, PAN Hongshuai1,*()()   

  1. 1 Department of General Surgery, Qinghai Provincial People’s Hospital, Xining 810007, Qinghai, China
    2 Department of Cardiology, Qinghai Provincial People’s Hospital, Xining 810007, Qinghai, China
  • Received:2025-06-30 Revised:2025-09-08 Online:2026-02-28 Published:2026-02-10
  • Contact: E-mail: 164161645@qq.com
  • Supported by:
    National Natural Science Foundation of China(82260412);2024 Kunlun Talents High-end Innovation and Entrepreneurship Talents of Qinghai Province (Qingrencai Zi [2025] 5);Qinghai Provincial People’s Hospital-Soochow University Joint Training Program of High-Level Health Personnel Project(2025-qhsrmyysd-01);Guiding Project of Qinghai Provincial Health Commission(2020-wjzdx-27)

Abstract:

Hepatic alveolar echinococcosis is a zoonotic parasitic disease that is known as the parasite cancer. Lesions of hepatic alveolar echinococcosis tend to grow along the intrahepatic blood vessels, and large lesions may directly invade or compress adjacent portal veins, hepatic vein, trunk, and the post-hepatic segment of the inferior vena cavar esulting in that the majority of patients with end-stage hepatic alveolar echinococcosis are complicated with cardiac cirrhosis, Budd-Chiari syndrome, or portal hypertension at varying degrees. This not only increases the difficulty in diagnosis and treatment for hepatic alveolar echinococcosis, but also raises the cost of disease treatment. Currently, the pathogenesis of hepatic alveolar echinococcosis induced portal hypertension, Budd-Chiari syndrome, and cardiac cirrhosis is not fully understood, and there are still controversies regarding diagnosis and treatment of these complications. This article provides a brief overview of the clinical symptoms induced by hepatic alveolar echinococcosis, including cardiac cirrhosis, Budd-Chiari syndrome, and portal hypertension.

Key words: Alveolar echinococcosis, Cardiac cirrhosis, Budd-Chiari syndrome, Portal hypertension, Liver fibrosis

CLC Number: