Investigation on human intestinal helminth infection in urban areas of Henan Province in 2015

Abstract

Abstract:

Objective To understand the endemic status of intestinal helminth infection in urban residents of Henan Province. Methods According to the protocol of The Third National Survey on Major Human Parasitic Diseases, the random cluster sampling method was used to select 62 residents committees as the survey spots from 37 counties in 14 prefectures, including Anyang, Hebi, Jiaozuo, etc., from January to May, 2015. Fecal samples were collected from residents aged > 1 year and detected by the Kato-Katz thick smear method. Cluster analysis was performed on families with Enterobius vermicularis infection. Results A total of 15 893 residents were examined, the total infection rate was 1.09% (174/15 893), and the standardized rate was 1.08%, 6 species of intestinal helminths were found, all showing light infection. No co-infection cases were found. E. vermicularis had the highest infection rate (0.92%, 147/15 893) （χ² = 117.648, P < 0.01), followed by Ascaris lumbricoides （0.07%, 11/15 893）, Ancylostoma sp. （0.06%, 10/15 893）, Trichuris trichiura（0.03%, 4/15 893）, and Strongyloides stercoralis as well as Clonorchis sinensis （0.01%, 1/15 893）. Among the 14 prefectures, the infection rate was highest in Luoyang （3.40%, 17/500） and lowest in Sanmenxia (0.20%, 1/501). There was no significant difference in the infection rate between males (1.03%, 77/7 477) and females (1.15%, 97/8 416). The population of 60- years had the highest infection rate (1.64%, 1/1 895) (χ² = 17.698, P < 0.05); the population of 50- years were detected with 6 species, which was the highest among age groups. The population of high school or above had the highest infection rate (1.48%, 58/3 912), significantly differed from preschool children （χ² = 8.145, P < 0.01). There was a significant difference in infection rate among different educational groups （χ² = 12.135, P < 0.05）. The medical personnel had the highest infection rate （4.76%, 10/210）, inclusive of E. vermicularis. C. sinensis and S. stercoralis were only found in farmers. There was a significant difference in infection rate among different occupations （χ² = 34.534, P < 0.05). A total of 147 cases of E. vermicularis infection were distributed in 124 households, and the results of the binomial distribution shows that the infection of E. vermicularis presented a characteristic of households clustering. Conclusion The infection of E. vermicularis is relatively high in urban areas of Henan Province.

Key words: Helminths, Henan Province, Urban area, Epidemiological investigation

CLC Number:

R532

Ya-lan ZHANG, Yan-kun ZHU, Wei-qi CHEN, Yan DENG, Xi-meng LIN, Peng LI, Hong-wei ZHANG, Bian-li XU. Investigation on human intestinal helminth infection in urban areas of Henan Province in 2015[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2018, 36(2): 135-139.

Figures/Tables 3

Table 1

Intestinal helminth infection rate in urban inhabitants from different survey cities of Henan in 2015

地区Prefecture	调查人数No. examined	蛲虫 E. vermicularis			蛔虫 A. lumbricoides			钩虫 Ancylostoma sp.			鞭虫 T. trichiura			粪类圆线虫 S. stercoralis			华支睾吸虫 C. sinensis			合计 Total
地区Prefecture	调查人数No. examined	感染人数No.cases	感染率/%Infection rate/%	标化感染率/%Standardized infection rate/%	感染人数No. cases	感染率/%Infection rate/%	标化感染率/%Standardized infection rate/%	感染人数No. cases	感染率/%Infection rate/%	标化感染率/%Standardized infection /%	感染人数No. cases	感染率/%Infection rate/%	标化感染率/%Standardized infection rate/%	感染人数No. cases	感染率/%Infection rate/%	标化感染率/%Standardized infection rate/%	感染人数No. cases	感染率/%Infection rate/%	标化感染率/%Standardized infection /%	感染人数No. cases	感染率/%Infection rate/%	标化感染率/%Standardized infection rate/%
安阳Anyang	532	7	1.32	1.52	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	7	1.32	1.52
鹤壁Hebi	1 001	6	0.60	0.52	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	6	0.60	0.52
焦作Jiaozuo	1 586	23	1.45	1.33	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	23	1.45	1.33
开封Kaifeng	1 353	7	0.52	0.49	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	7	0.52	0.49
洛阳Luoyang	500	17	3.40	3.18	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	17	3.40	3.18
漯河Luohe	1 000	0	0.20	0.12	0	0	0	0	0	0	2	0.20	0.12	0	0	0	0	0	0	2	0.20	0.12
平顶山Pingdingshan	1 049	15	2.00	1.65	4	0.38	0.34	1	0.10	0.14	1	0.10	0.04	0	0	0	0	0	0	21	2.00	1.65
濮阳Puyang	1 000	16	1.70	1.98	1	0.10	0.13	0	0	0	0	0	0	0	0	0	0	0	0	17	1.70	1.98
三门峡Sanmenxia	501	1	0.20	0.11	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0.20	0.11
信阳Xinyang	1 015	1	0.20	0.16	1	0.10	0.08	0	0	0	0	0	0	0	0	0	0	0	0	2	0.20	0.16
许昌Xuchang	1 059	0	0.28	0.23	3	0.28	0.23	0	0	0	0	0	0	0	0	0	0	0	0	3	0.28	0.23
郑州Zheng-zhou	2 535	23	1.03	1.12	0	0	0	2	0.08	0.06	0	0	0	1	0.04	0.03	0	0	0	26	1.03	1.12
周口Zhou-kou	1 512	25	1.98	1.83	2	0.13	0.14	1	0.07	0.04	1	0.07	0.05	0	0	0	1	0.07	0.05	30	1.98	1.83
驻马店Zhumadian	1 250	6	0.96	1.03	0	0	0	6	0.48	0.44	0	0	0	0	0	0	0	0	0	12	0.96	1.03
合计 Total	15 893	147	0.92	0.94	11	0.07	0.06	10	0.06	0.06	4	0.03	0.02	1	0.01	0.01	1	0.01	0	174	1.09	1.08

Table 1

Table 2

Intestinal helminth infection rate by different gender, age, education and occupation groups in Henan in 2015

特征 Feature		检查人数 No. examined	蛲虫 E. vermicularis		蛔虫 A. lumbricoides		钩虫 Ancylostoma sp...		鞭虫 T. trichiura		粪类圆线虫 S. stercoralis		华支睾吸虫 C. sinensis		合计 Total
特征 Feature		检查人数 No. examined	感染人数No. cases	感染率/%Infection rate/%	感染人数No. cases	感染率/%Infection rate/%	感染人数No. cases	感染率/%Infection rate/%	感染人数No. cases	感染率/%Infection rate/%	感染人数No. cases	感染率/%Infection rate/%	感染人数No. cases	感染率/%Infection rate/%	感染人数No. cases	感染率/%Infection rate/%
性别 Gender	男性 Males	7 477	63	0.84	5	0.07	6	0.08	2	0.03	0	0	1	0.01	77	1.03
	女性 Females	8 416	84	1.00	6	0.07	4	0.05	2	0.02	1	0.01	0	0	97	1.15
年龄 Age	0~	2 744	15	0.55	2	0.07	2	0.07	0	0	0	0	0	0	19	0.69
年龄 Age	10~	1 388	16	1.15	0	0	1	0.07	0	0	0	0	0	0	17	1.22
	20~	1 978	14	0.71	0	0	2	0.10	0	0	0	0	0	0	16	0.81
	30~	1 961	20	1.02	1	0.05	0	0	0	0	0	0	0	0	21	1.07
	40~	2 485	17	0.68	2	0.08	1	0.04	0	0	0	0	0	0	20	0.80
	50~	2 307	29	1.26	3	0.13	1	0.04	1	0.04	1	0.04	1	0.04	36	1.56
	60~	1 895	25	1.32	2	0.11	1	0.05	3	0.16	0	0	0	0	31	1.64
	70~	1 135	11	0.97	1	0.09	2	0.18	0	0	0	0	0	0	14	1.23
文化程度Education	学龄前儿童 Preschool children	1 503	5	0.33	2	0.13	1	0.07	0	0	0	0	0	0	8	0.53
	文盲 Illiteracy	918	6	0.65	1	0.11	0	0	0	0	1	0.11	0	0	8	0.87
	小学 Primary school	3 504	34	0.97	4	0.11	2	0.06	3	0.09	0	0	0	0	43	1.23
	初中 Junior high school	6 056	46	0.76	3	0.05	6	0.10	1	0.02	0	0	1	0.02	57	0.94
	高中及以上 Senior high school or above	3 912	56	1.43	1	0.03	1	0.03	0	0	0	0	0	0	58	1.48
职业 Occupation	医务人员Medical personnel	210	10	4.76	0	0	0	0	0	0	0	0	0	0	10	4.76
	教师 Teacher	145	3	2.07	0	0	0	0	0	0	0	0	0	0	3	2.07
	学龄前儿童Preschool children	1 503	5	0.31	2	0.12	1	0.06	0	0	0	0	0	0	8	0.49
	农民 Farmer	5 788	48	0.83	7	0.12	6	0.10	3	0.05	1	0.02	1	0.02	66	1.14
	学生 Student	2 572	26	1.06	0	0	1	0.04	0	0	0	0	0	0	27	1.10
	职工Staff	2 185	15	0.69	1	0.05	1	0.05	0	0	0	0	0	0	17	0.78
	其他 Others	3 490	40	1.15	1	0.03	1	0.03	1	0.03	0	0	0	0	43	1.23

Table 2

Table 3

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每户感染例数 No. infected per household	实际户数 Actual frequency	理论户数 Theoretical frequency
0	5 639	5 618.6
1	110	142.6
2~5	14	1.8
合计Total	5 763	5 763.0

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