Epidemiological investigation on echinococcosis in Huangnan Tibetan Autonomous Prefecture of Qinghai Province

Abstract

Abstract:

To analyze the prevalence of hydatid disease in Huangnan Tibetan Autonomous Prefecture of Qinghai, two to three villages were randomly selected in each of the Henan County, Jianzha County, Tongren County, and Zeku County in Huangnan of Qinghai. Ultrasound examination was performed for local residents aged > 1 year. Animal echinococcosis was investigated by visceral anatomy, and ELISA was used to detect echinococcosis antigen in fecal samples of stray dogs. In this study, a total of 11 231 residents received ultrasound examination, of whom 77 were positive for hydatid cysts with a morbidity rate of 0.69%. The prevalence of hydatid disease was highest in Zeku County (2.12%, 68/3 213), followed by Henan County (0.26%, 9/3 430). The prevalence of hydatid disease in females was 0.72% (44/6 094), and 0.64% (33/5 137), respectively. Among various occupations, the herdsmen had the highest prevalence rate of 0.83% (61/7 338). Among age groups, the human hydatid disease prevalence rate was relatively higher in populations of 50-59 years (1.25%, 9/721), 60-69 years (1.96%, 13/663) and 30-39 years (0.91%, 24/2 637). In addition, the prevalence of hydatid disease was higher in the uneducated (0.66%) and in those at the primary school level (0.79%). The residents that settled in winter and was nomadic in summer had the highest prevalence (1.10%, 70/6 391), followed by the nomadic population (0.62%, 6/965). There were significant prevalence differences in terms of region, age, living style and educational level (P < 0.05), rather than in gender, occupation (P > 0.05). Of the 1 282 dog fecal samples collected, the fecal antigen positive rate was 11.70%（150/1 282）, with a significant regional difference (P < 0.05). Among the 3 525 intermediate host sheep, the hydatid infection rate was 2.13% (75/3 525), with a significant regional difference (P < 0.05). The results indicats a hydatid disease morbidity of 0.69% in residents and 2.13% in sheep, and the antigen positive rate in dogs feces is 11.70% in Huangnan Tibetan Autonomous Prefecture of Qinghai Province.

Key words: Qinghai, Huangnan, Hydatid disease, Epidemiology, Investigation

CLC Number:

R532.32

Xiao MA, Hu WANG, Shi-lei CHENG, Jing-xiao ZHANG, Yong-shun WANG, Yu-fang LIU, Jun-ying MA, Hui-xia CAI, Pei-yun LIU, Xiu-min HAN, Hai-qing LIU, Yan-mei ZHAO, Wei WANG, Wen LEI, Rui DU, Guo-ming SU, Na LIU, Ke-mei SHI, Xiong-ying ZHANG. Epidemiological investigation on echinococcosis in Huangnan Tibetan Autonomous Prefecture of Qinghai Province[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2017, 35(5): 512-514.

Figures/Tables 2

References 12

[1]	韩秀敏, 王虎, 蔡辉霞, 等. 青海省达日县棘球蚴病流行病学调查[J]. 中国寄生虫学和寄生虫病杂志, 2009, 27(1): 22-26.
[2]	程时磊, 王虎, 马宵, 等. 2012年青海省玉树藏族自治州棘球蚴病流行调查[J]. 中国寄生虫学和寄生虫病杂志, 2016, 32(6): 547-551.
[3]	王国强, 于竞进, 王宇, 等. 全国包虫病流行情况调查报告[M]. 上海: 上海科技科学出版社. 2016: 14-15.
[4]	侯碧波, 张小军. 青海统计年鉴[M]. 北京: 中国统计出版社, 2016: 85-94.
[5]	Wang Q, Yu WJ, Zhong B, et al. Seasonal pattern of Echinococcus re-infection in owned dogs in Tibetan communities of Sichuan, China and its implications for control[J]. Infect Dis Poverty, 2015, 5: 60.
[6]	Wang Q, Huang Y, Huang L, et al. Review of risk factors for human echinococcosis prevalence on the Qinghai-Tibet Plateau, China: a prospective for control options[J]. Infect Dis Poverty, 2014, 3: 3.
[7]	Restrepo AMC, Yang YR, Mcmanus DP, et al. The landscape epidemiology of echinococcoses[J]. Infect Dis Poverty, 2016, 5: 13.
[8]	齐颜凤, 伍卫平. 棘球蚴病流行病学研究进展[J]. 中国寄生虫学和寄生虫病杂志, 2013, 31(2): 143-148.
[9]	范道勇, 刘涛, 王再跃, 等. 四川甘孜藏族自治州2012年儿童棘球蚴病血清学调查[J]. 中国寄生虫学和寄生虫病杂志, 2014, 32(3): 197-199.
[10]	王庆华, 尚文杰, 赵春桃, 等. 2007-2011年甘南藏族自治州棘球蚴病流行现状分析[J]. 中国寄生虫学和寄生虫病杂志, 2015, 33(1): 45-48.
[11]	何叶, 尹家祥. 棘球蚴病流行因素分析[J]. 中国热带医学, 2017, 17(4): 418-420.
[12]	刘辉, 肖宁, 杨诗杰, 等. 青藏高原地区犬棘球绦虫感染的流行病学特征[J]. 中国血吸虫病防治杂志, 2017, 29(2): 129-138.

特征		B超检查
特征		检查人数	阳性人数	阳性率/%
地区	河南县	3 430	9	0.26
	尖扎县	1 388	0	0
	同仁县	3 200	0	0
	泽库县	3 213	68	2.12
	性别	男性	5 137	33	0.64
女性		6 094	44	0.72
职业		牧民	7 338	61	0.83
	宗教人士	740	3	0.41
	家务人员	2 895	12	0.41
	学生	195	1	0.51
	其他	63	0	0
	年龄/岁	0~9	742	0	0
10~19		1 202	3	0.25
20~29		2 753	14	0.51
30~39		2 647	24	0.91
40~49		1 922	13	0.68
50~59		721	9	1.25
60~69		663	13	1.96
≥70		581	1	0.17
文化程度		文盲	2 709	18	0.66
	小学	7 432	59	0.79
	初中	839	0	0
	高中	184	0	0
	大专及以上	52	0	0
	居住方式	定居	3 875	1	0.03
冬季定居夏季游牧		6 391	70	1.10
游牧		965	6	0.62

地区	羊			犬
地区	检查份数	阳性检出数	检出率/%	检查粪数	抗原阳性数	阳性率/%
河南县	1 000	17	1.70	320	54	16.88
尖扎县	500	0	0.00	322	10	3.11
同仁县	1 000	3	0.30	320	52	16.25
泽库县	1 025	55	5.37	320	34	10.63
合计	3 525	75	2.13	1 282	150	11.70

[1]	KUI Yan, XUE Chuizhao, WANG Xu, LIU Baixue, WANG Ying, WANG Liying, YANG Shijie, HAN Shuai, XU Xuenian. Progress of echinococcosis control in China, 2022 [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2024, 42(1): 8-16.
[2]	LI Chunyan, ZHANG Fuyan, SHI Peng, TIAN Fengyuan. Analysis of imported malaria epidemic in Zigong City of Sichuan Province from 2011 to 2023 [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2024, 42(1): 129-133.
[3]	JI Penghui, JIANG Tiantian, HE Zhiquan, WANG Dan, YUE Sining, LI Suhua, YANG Chengyun, WANG Hao, ZHANG Hongwei, ZHOU Ruimin. Molecular epidemiological investigation of Babesia infection in ticks parasitized on domestic animals in Xinyang, Henan Province [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2023, 41(5): 567-572.
[4]	LI Benfu, YANG Jing, YANG Jinyu, LUO Ruijuan, ZHU Binlin, CHEN Tailin, ZHANG Lijuan, LI Xueyao, YAN Xinliu, ZI Jinrong, PENG Jia, WANG Zhengqing, LI Jianxiong, CAI Xuan, XU Qian, WU Fangwei, YANG Yaming. Epidemiological investigation and case retrospective analysis of echinococcosis in Dali Prefecture, Yunnan Province [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2023, 41(5): 573-578.
[5]	CAI Zhanghuang, ZHANG Zhiping, ZHUO Mingying, GUO Liping, FU Zhihui, LIU Yiruo. Trematode egg internal transcribed space-2 sequence based analysis for diagnosis of Opisthorchis viverrin and Opisthorchis sinensis infections [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2023, 41(4): 427-433.
[6]	LI Xiaoli, LI Shaogang, WU Zhaoyong. Clinical characteristics of patients with intestinal Diphyllobothrium tapeworm infection [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2023, 41(4): 459-463.
[7]	ZHANG Juan, TAO Hong, LI Yanzhong, WANG Tingting, YANG Jingjing, XIANG Yibin, CHEN Yishan, ZHOU Xiaomei. Survey on Angiostrongylus cantonensis infection in common snails in Yunnan Province from 2017 to 2022 [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2023, 41(4): 464-469.
[8]	WANG Wei, CAI Huixia. Surveillance of echinococcosis in Qinghai Province in 2020 [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2023, 41(3): 319-324.
[9]	KUI Yan, XUE Chuizhao, WANG Xu, LIU Baixue, WANG Ying, WANG Liying, YANG Shijie, HAN Shuai, WU Weiping, XIAO Ning. Progress of echinococcosis control in China, 2021 [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2023, 41(2): 142-148.
[10]	SUN Hui, LI Li, YAN Hongbin, LI Xiurong, FU Baoquan, JIA Wanzhong. Research progress on molecular markers and epidemiology of Echinococcus ortleppi [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2023, 41(2): 213-218.
[11]	GUO Zhanjing, ZHANG Shiyong, LIU Li. Epidemiological investigation on the recurrence of visceral leishmaniasis in Shijiazhuang City [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2023, 41(2): 241-244.
[12]	LIU Jiancheng, XU Yan, WANG Longjiang, KONG Xiangli, WANG Yongbin, LI Yuejin. Surveillance on imported malaria in Linyi City of Shandong Province from 2015 to 2021 [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2023, 41(2): 249-252.
[13]	LI Dan, JI Fengying, WANG Longjiang, WANG Yongbin, LI Yuejin, YAN Ge, XU Yan, BU Xiuqin, ZHANG Benguang. Anisakis infection in marine fishes and resident awareness of anisakiasis in Qingdao in 2021 [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2023, 41(1): 52-58.
[14]	LIU Yu-ying, ZHANG Tian-tian, MA Xiao, LEI Wen, MA Bing-cun, LIU Shou. Awareness and influencing factors of knowledge on echinococcosis prevention and control among adults in Qinghai Province [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2022, 40(6): 723-729.
[15]	ZHANG Jing-xiao, SHI Ke-mei, LIU Yu-fang, ZHAO Cun-zhe, ZHAN Pei-zhen, WANG Wei, LIU Jia, LIU Na, LEI Wen, ZHANG Qing, ZHANG Xiong-ying, MA Xiao, CAI Hui-xia, MA Jun-ying. Surveillance on soil-transmitted helminth infection in residents in Qinghai Province during 2016—2020 [J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2022, 40(6): 737-741.