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The Immunomodulatory Role of C-type Lectin Receptors in Parasitic Infection

LIU Bo-yu, LI Pan, YANG Gui-lian*   

  1. College of Animal Science and Technology, Jilin Agricultural University; Jilin Provincial Engineering Research Center of Animal Probiotics, Changchun 130118, China
  • Online:2015-06-30 Published:2015-09-08

Abstract:

【Abstract】 C-type lectins are a group of Ca2+-dependent glycan-binding proteins. The C-type lectin receptors (CLRs) recognize carbohydrate ligands in a Ca2+-dependent manner. Recent research has demonstrated that CLRs could recognize glycoproteins and activate downstream immune responses. This review summarizes the roles of several CLRs in parasitic infection.

Key words: C-type lectin receptor, Parasite, Infection, Immune evasion