Research Advance on Toxoplasma gondii Rhoptry Protein 2 Family as Candidate Vaccine Molecules

Abstract

Abstract:

【Abstract】 Toxoplasma gondii rhoptry protein 2 family (ROP2 family), secreted by the rhoptry， plays an important role in T. gondii invasion of host cells and its virulence. The ROP2 family members include ROP2, ROP4, ROP5, ROP8, ROP13,ROP16, ROP17,and ROP18. Recent studies have found that these members are potential vaccine candidates against toxoplasmosis, and can induce the protective immunity of the host. This paper reviews the research advance on the ROP2 family members as DNA or protein vaccines against toxoplasmosis.

Key words: Toxoplasma gondii, Rhoptry protein 2 family, DNA vaccine, Protein vaccine

LI Run-hua, ZHANG Tie-e, YIN Guo-rong*. Research Advance on Toxoplasma gondii Rhoptry Protein 2 Family as Candidate Vaccine Molecules[J]. .

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Research Advance on Toxoplasma gondii Rhoptry Protein 2 Family as Candidate Vaccine Molecules

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