Abstract:  Lymphatic filariasis used to highly prevalent in 69 counties （cities） with 29 million people at the risk of infection in Hubei Province. There were 2 million people infected either by B. malayi or W. bancrofti that 1.6 million microfilaremia cases and 0.4 million chronic patients. The average rate of microfilaremia among population was 5.94%. Anopheles sinensis and Culex quinquefasciatus were the principal transmitting vectors. Since 1970s，with the strategy of taking elimination of infection source as a major focus，the average rate of the microfilaremia reduced to 0.048% with a village as the unit in 1988，and reached the standard of transmission interruption. With continuous surveillence for over a decade，the province reached the goal of filariasis elimination in 2001. This paper reviews the prevalence，control and elimination process of filariasis in Hubei Province since 1950s.

Key words: Filariasis, Prevalence, Control, Elimination, Hubei