Abstract: Objective To understand the epidemiological features of the hospitalized cases with Clonorchis sinensis infection in Guigang City of Guangxi Region. Methods Fecal samples were collected from patients each with 30-50 g and examined by sedimentation technique. Number of eggs was counted in randomly selected cases by Stoll's method. With the number of eggs per gram（EPG）feces, light, medium and heavy intensity of infection were identified as EPG≤500, 501～5 000 and >5 000 respectively. Results Among 2 175 cases with clonorchis eggs, 1 244 cases showed clinical complications（57.2%）. The average EPG in 61 cases counted was 3 055，34（55.7%）showed medium or heavy intensity of infection. The cases distributed in 80% of the townships, more concentrated in 2 towns and 1 farm. The patients aged between 3 to 76 years old with a ratio of male to female 3.6 ∶ 1. 45.5% of the cases were farmers. 1 308 cases（60.1%） were Zhuang Minority. The number of cases seeking medical treatment increases year by year since mid-1980s. 66.0% of the cases had a habit of raw fish-eating. Conclusion Clonorchiasis sinensis widely distributes in Guigang City, number of cases admitted in hospitals increases yearly.

Key words: Clonorchis sinensis, Complication, Distribution, Feature