CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES ›› 2022, Vol. 40 ›› Issue (4): 436-440.doi: 10.12140/j.issn.1000-7423.2022.04.003

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Research progress of stem cells in driving schistosome growth and development

WANG Ji-peng*()   

  1. State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200438, China
  • Received:2022-04-27 Revised:2022-05-30 Online:2022-08-30 Published:2022-09-07
  • Contact: WANG Ji-peng E-mail:jipengwang@fudan.edu.cn
  • Supported by:
    National Key Research and Development Program of China(2021YFC2300800);National Key Research and Development Program of China(2021YFC2300803)

Abstract:

Stem cells are unspecialized cells that have the ability of self-renewal and differentiation into multiple cell types, which commit the tissue turnover and repair of the body. In recent years, the function of stem cells in schistosomes and other parasitic flatworms has attracted attention and a series of discoveries have been made. This review summarized the advances and tools in schistosome stem cell research to provide valuable information for understanding the basic biology of schistosome growth and development as well as the establishment of intermediate and definitive hosts.

Key words: Schistosoma, Stem cell, Cell differentiation, Tissue turnover, Growth and development

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