CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES ›› 2019, Vol. 37 ›› Issue (4): 399-405.doi: 10.12140/j.issn.1000-7423.2019.04.005
• ORIGINAL ARTICLES • Previous Articles Next Articles
Ying DONG1,*(), Shu-ping LIU1,2, Yan-chun XU1, Yan LIU1, Yan DENG1, Meng-ni CHEN1
Received:
2019-01-28
Online:
2019-08-30
Published:
2019-09-05
Contact:
Ying DONG
E-mail:luxidongying@126.com
Supported by:
CLC Number:
Ying DONG, Shu-ping LIU, Yan-chun XU, Yan LIU, Yan DENG, Meng-ni CHEN. Mutations and predicted structure change of G6PD isolated from a patient with primaquine-induced hemolysis in Yunnan Province[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2019, 37(4): 399-405.
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URL: https://www.jsczz.cn/EN/10.12140/j.issn.1000-7423.2019.04.005
Fig. 1
PCR products of G6PD exon fragments amplified from the blood sample of a P. vivax infected patient with primaquine-induced hemolysis M: DNA marker; 1, 5, 10, 15: The 1st round PCR blank control (no template); 6, 11, 16: The 2nd round PCR blank control; 2-4: The PCR products of G6PD exon2; 7-9: The PCR products of G6PD exon3-7; 12-14: The PCR products of G6PD exon8-9; 17-19: The PCR products of G6PD exon10-13
Table 1
Model parameters of predicted 3D structure of G6PD identified from a hemolysis patient infected with P. vivax
氨基酸序列 | 二聚体Dimers | 四聚体Tetramers | |||||||
---|---|---|---|---|---|---|---|---|---|
Amino acid sequence | 入模氨基酸范围Amino acid position | GMQE | QMEAN | 一致性/% Identity/% | 入模氨基酸范围Amino acid position | GMQE | QMEAN | 一致性/% Identity/% | |
参比模型Reference model | 6e07.1.A | 1qki.1.A | |||||||
NC_000023.11 | 28-513 | 0.97 | -0.64 | 99.22 | 12-493 | 0.98 | -1.49 | 99.36 | |
X55448.1 | 28-513 | 0.97 | -0.65 | 98.83 | 12-493 | 0.98 | -2.17 | 98.56 | |
homo2608 | 28-513 | 0.97 | -0.66 | 99.42 | 12-493 | 0.98 | -2.26 | 99.19 |
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