中国寄生虫学与寄生虫病杂志 ›› 2009, Vol. 27 ›› Issue (1): 17-79.

• 综述 • 上一篇    下一篇

多房棘球蚴病诊断抗原研究进展

周必英1,2,陈雅棠1*,李文桂1*   

  1. 1 重庆医科大学附属第一医院传染病寄生虫病研究所,重庆 400016;2 贵州省遵义医学院寄生虫学教研室,遵义 563003
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2009-02-28 发布日期:2009-02-28
  • 通讯作者: 陈雅棠,李文桂

Research Progress in Antigens for the Diagnosis of Alveolar Echinococcosis

ZHOU Bi-ying1,2, CHEN Ya-tang1*, LI Wen-gui1*   

  1. 1 Institute of Infectious and Parasitic Diseases,the First Affiliated Hospital,Chongqing Medical University,Chongqing 400016,China;2 Department of Parasitology,Zunyi Medical College,Zunyi 563003,China
  • Received:1900-01-01 Revised:1900-01-01 Online:2009-02-28 Published:2009-02-28
  • Contact: CHEN Ya-tang, LI Wen-gui

摘要: 多房棘球绦虫特异性和保护性抗原的研究是多房棘球蚴病免疫和诊断的基础。由于天然抗原来源有限,应用受到限制,重组抗原的研制则可解决质量控制和抗原来源的问题。本文就近年来国内外对多房棘球蚴病诊断抗原尤其是重组抗原的研究进展进行了综述。

关键词: 多房棘球绦虫, 多房棘球蚴病, 免疫诊断

Abstract: Specific antigens of Echinococcus multilocularis is essential for the diagnosis of alveolar echinococcosis and vaccine development. Because of the limited source of nature antigen, its application is restricted. The development of recombinant antigens can provide large amount of antigen under effective quality control. This review summarizes the recent progress in antigen research, especially the recombinant antigen used for diagnosis of the disease.

Key words: Echinococcus multilocularis, Alveolar echinococcosis, immunodiagnosis